Integration of paper spray ionization high‐field asymmetric waveform ion mobility spectrometry for forensic applications
نویسندگان
چکیده
منابع مشابه
Separation of opiate isomers using electrospray ionization and paper spray coupled to high-field asymmetric waveform ion mobility spectrometry.
One limitation in the growing field of ambient or direct analysis methods is reduced selectivity caused by the elimination of chromatographic separations prior to mass spectrometric analysis. We explored the use of high-field asymmetric waveform ion mobility spectrometry (FAIMS), an ambient pressure ion mobility technique, to separate the closely related opiate isomers of morphine, hydromorphon...
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A surface ionization (SI) source was designed and constructed for ion mobility spectrometry (IMS). Compared with a conventional (63)Ni source, the surface ionization source is as simple and reliable, has an extended dynamic response range, is more selective in response, and does not have regulatory problems associated with radioactive ionization sources. The performance of this SI-IMS was evalu...
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Miniaturized ultra high field asymmetric waveform ion mobility spectrometry (ultra-FAIMS) combined with mass spectrometry (MS) has been applied to the analysis of standard and tryptic peptides, derived from α-1-acid glycoprotein, using electrospray and nanoelectrospray ion sources. Singly and multiply charged peptide ions were separated in the gas phase using ultra-FAIMS and detected by ion tra...
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BACKGROUND Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) is a material analysis technology which develops very fast in recent years. Resolution is an important factor used to estimate the performance of this technology. With greater resolution, it's always easier to separate complex mixtures. RESULTS A method to increase the resolution of FAIMS is put forward which focuses ions ...
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This review highlights and critically assesses forensic applications in the developing field of ambient ionization mass spectrometry. Ambient ionization methods permit the ionization of samples outside the mass spectrometer in the ordinary atmosphere, with minimal sample preparation. Several ambient ionization methods have been created since 2004 and they utilize different mechanisms to create ...
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ژورنال
عنوان ژورنال: Rapid Communications in Mass Spectrometry
سال: 2018
ISSN: 0951-4198,1097-0231
DOI: 10.1002/rcm.8068